Trimethoprim is a bacteriostatic antibiotic used mainly in the prophylaxis and treatment of urinary tract infections.Target: DHFRTrimethoprim (TMP), an inhibitor of dihydrofolate reductase, decreases the level of tetrahydrofolate supplying one-carbon units for biosynthesis ofnucleotides, proteins, and panthotenate . TMP a provocat inducerea DNAK, DNAJ, Groel, ClPB și IBPA/B HSPS. Printre aceste HSP -uri, IBPA/B au fost induse cel mai eficient de TMP și coagregate cu proteinele insolubile

densitate:

1.252

boiling punct:

526 OC la 760 mmhg

melting punct:

199-203 ℃

flash Point:

271.9 Oc

storage temperatură:

2-8 ° c

refractive Index:

1.6000 (estimare)

soluBility:

dmso: solubble <0.1 g/100 ml la 24 OC

Stabilitate:

stable. Incompatibil cu agenți puternici de oxidare, acizi.